Panama Canal Collection

Royal Caribbean's Panama Canal sailings, cruise through one of the man made wonders of the world.  

From Caribbean islands and Mexican coastal towns to jungle views, taking you from one ocean to another through a sliver of engineering ingenuity.  Go through 12 locks at 3 different points, the Miraflores Locks, the Pedro Miguel to the Gatun Locks.

Enjoy a bucket list cruise onboard Royal Caribbean and let the world float by.

Show more
  • Serenade of the Seas Royal Caribbean

    Panama Canal Collection

    13 nights
    Cruise Line: Royal Caribbean Ship: Serenade of the Seas Departure Date: 23 Apr 2026 Price From: £1789 pp Type: Fly Cruise

    Itinerary: fly london to panama city, overnight at hotel - overnight at hotel - embark ship - panama canal, panama - puntarenas, costa rica - huatulco, mexico - puerto vallarta, mexico - los angeles - disembark ship for overnight flight to london

    Interior:£1789 pp Oceanview:£2029 pp Balcony:£2349 pp Suite:£2949 pp

    Return flights from London

    2 nights 4* B&B stay in Panama City

    10 nights' full-board cruise

  • Serenade of the Seas Royal Caribbean

    Panama Canal Collection

    15 nights
    Cruise Line: Royal Caribbean Ship: Serenade of the Seas Departure Date: 18 Sep 2025 Price From: £1889 pp Type: Fly Cruise

    Itinerary: fly london to san diego, overnight at hotel - embark ship - puerto vallarta, mexico - huatulco, mexico - puntarenas, costa rica - panama canal, panama - cartagena, colombia - miami - disembark ship for overnight flight to london

    Interior:£1889 pp Oceanview:£2139 pp Balcony:Call us Suite:Call us

    Return flights from London

    one night 4* hotel stay in San Diego

    13 nights full-board cruise